Uso de la cistatina C como biomarcador para estimar la tasa de filtración glomerular

نویسندگان

چکیده

Glomerular filtration rate (GFR) is routinely estimated using endogenous biomarkers due to the complexity of direct measurement methods. Cystatin C a protease inhibitor produced in all nucleated cells. It freely filtered and then catabolized by renal tubular Therefore, plasma concentration cystatin depends primarily on GFR. Serum less affected muscle mass, diet, race, gender age than creatinine. In general population, equations estimate GFR based do not have better performance those However, formulas that combine creatinine are more accurate precise. Estimation could be useful populations which value may biased, such as people with extremely low or high cirrhosis chronic cardiorenal syndrome. Due its higher cost comparison creatinine, we recommend measuring these clinical situations when estimation required.

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ژورنال

عنوان ژورنال: Revista Medica De Chile

سال: 2021

ISSN: ['0717-6163', '0034-9887']

DOI: https://doi.org/10.4067/s0034-98872021000100098